Proteomics and Genomics in Personalized Medicine

The study of the full set of genes in a cell's genome is known as genomics, whereas the study of the entire collection of proteins generated by the cell is known as proteomics. Instead of classifying patients into treatment groups based on phenotype, precision medicine includes explicitly adapting treatment to the individual characteristics of the patient. Based on a thorough understanding of an individual's unique biology, it will cover both health and disease, as well as their impact on predisposition, screening, diagnosis, prognosis, pharmacogenomics, and surveillance. Scientists no longer have to depend solely on proteomic or genomic information in isolates because of significant advances in sequencing technology in recent years. Proteogenomics studies the function of protein variations in biological systems and disease pathologies by combining mass spectrometry (MS) techniques with high-throughput next-generation sequencing (NGS) technology. Researchers are interested to explore where proteogenomics will take precision medicine in the future, given recent developments in the discipline.

• Multiple reaction monitoring (MRM)
• Big data problems
• Pharmacogenomics
• Protein- wide interactions
• Proteogenomics
• Sequencing