Precision medicine is a "developing approach to disease treatment and prevention that considers individual heterogeneity in genes, environment, and lifestyle." Precision medicine refers to the use of genetic and other technologies to define disease at a lower level, allowing for more specific targeting of disease subgroups with novel medicines. Genome sequencing has the potential to improve patient care by improving diagnostic sensitivity and allowing for more precise therapy targeting. To fully realise this promise, genomics tools designed for genetic discovery, such as DNA-sequencing technologies and analytic algorithms, must be tailored to meet clinical demands. Clinical genomics sits at the crossroads of population-based sequencing-led discovery genetics and traditional low-throughput techniques to genetic identification in patients. The global scientific and technological advancements in molecular biology have resulted in a new approach to biological challenges, ushering in a new era of scientific research in biology, chemistry, and physics, as well as novel medical procedures. The application of molecular biology methods to the diagnosis of a wide range of infectious and genetic diseases is today the foundation for medical practice.