Title: Personalized and precision medicine (PPM) can be established as a unique healthcare model through biodesign-driven and inspired biotech, translational applications. This approach aims to ensure human healthcare, wellness, and biosafety.
Abstract:
A new and upgraded approach to the diseased states and wellness, and to re-shape tomorrow’s healthcare whilst doing it today, resulted in a new global trend in the healthcare services, namely, Personalized and Precision Medicine (PPM). PPM as a Unique Entity demonstrating an integration of Fundamental, Healthcare & Life Scienc-es, Biodesign-driven BioTech, Translational ART and IT Armamentarium, is based on the new developmental strategy driven by Biomarkers- and Biotargeting-related biomachines. So, it would be extremely useful to integrate data harvesting from different databanks for applications such as pre-early predictive diagnostics, precise prognosti-cation and personalization of further treatment to thus provide more tailored measures for the diseases bodies and persons-at-risk resulting in improved outcomes and more cost effective use of the latest health care resources. PPM as being the Grand Challenge to forecast, to predict and to prevent is rooted in a big and a new SCIENCE generated by the achievements of (i) Systems & Synthetic Biology; (ii) Biodesign-driven Translational applications and Biotech-driven Biomanufacturing; (iii) Bioindustry and Biomarketing of the next step generation. The latter, being a Grand Brick laid into the frame of National Bioeconomy, says and confirms that the efficiency and efficacy of the Bioeconomy are determined and dictated by the innovative trends,generated by fresh knowledge and their transfer into the scientific, bioindustrial and social areas to maintain the national stability and extensive development of the country. The core strategic tool to operate the transdisciplinary approach is rooted in a unique tandem consisting of (i) inte-grated platforms of Fundamental Sciences (Basics) and innovative OMICs biotechnologies on one hand, and (ii) the algorithms of Bioinformatics, on the other one. Healthcare is undergoing a transformation, and it is imperative to leverage new technologies to support the advent of PPM. This is the reason for developing global scientific, clinical, social, and educational projects in the area of PPM and Tramed to elicit the content of the new trend. The latter would provide a unique platform for dialogue and collaboration among thought leaders and stakeholders in government, academia, industry, foundations, and disease and patient advocacy with an interest in improving the system of healthcare delivery on one hand and drug discovery, development, and translation, on the other one, whilst educating the policy community about issues where biomedical science and policy intersect.