Precision medicine is a technique for doctors to deliver and plan personalised care for their patients based on their genetics (or the genes in their cancer cells). It's also known as personalized medicine or personalized care. Precision medicine examines how a specific gene change (gene mutation) may affect a person's likelihood of developing a specific cancer, or how their genes (or genes in their cancer cells) may affect treatment if they already have cancer. Precision medicine is being used to determine which tests and treatments are best for certain cancers. Of course, the goal is to develop more precise medicine that reduces side effects while increasing therapeutic impact. However, the last 20 years have been marked by sophisticated scientific conceptual achievements that have been overshadowed by a lack of attention to the fundamental building blocks of implementation and the realities of patient care. Precision oncology will continue to make scientific advancements, but in order to make real changes for patients, worldwide collaboration and a holistic approach to the patient that extends beyond the lab are essential.